Hepatitis B: The Silent Infection 250 Million People Carry, Testing, Vaccine and Treatment

Most people with chronic hepatitis B feel completely well, but it can lead to cirrhosis and liver cancer. How it spreads, who should be tested and how to protect babies.

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Edited by Joshua Adebanjo, RN

Nurse giving a newborn a hepatitis B vaccine

Hepatitis B is a virus that infects the liver. The World Health Organization estimates that about 254 million people were living with chronic hepatitis B in 2022, and it causes more than a million deaths a year, mainly from cirrhosis and liver cancer. Most people with it do not know.

One injection in the first 24 hours of life can protect a baby from a virus that causes liver cancer decades later. That is the power of knowing about hepatitis B.

How it spreads

  • From mother to baby at birth, the most common route in many countries
  • Blood, including shared needles, unsterile medical or dental equipment, razors and tattoo equipment
  • Unprotected sex
  • It is not spread by hugging, sharing food or water, coughing or breastfeeding

Symptoms

Many people have no symptoms. Some develop acute illness weeks after infection, with tiredness, nausea, abdominal pain, dark urine and yellow skin or eyes (jaundice). Babies and young children who are infected are much more likely to develop lifelong chronic infection.

Who should be tested?

  • All pregnant women
  • People born in countries where hepatitis B is common
  • Partners and household members of someone with hepatitis B
  • People living with HIV or hepatitis C
  • People who inject drugs
  • Health workers
  • Anyone with abnormal liver tests

The main test is a blood test for hepatitis B surface antigen (HBsAg).

The vaccine: protection for life

The hepatitis B vaccine is safe and highly effective. WHO recommends that every baby receives a dose within 24 hours of birth, followed by further doses in infancy. Adults who were not vaccinated, including health workers, should get a full course.

For pregnant women with hepatitis B: the birth dose, sometimes with immunoglobulin and antiviral treatment in late pregnancy, can prevent the baby from being infected.

Treatment

There is no cure yet, but antiviral medicines such as tenofovir and entecavir can control the virus and greatly reduce the risk of liver damage and cancer. Not everyone needs treatment, but everyone with chronic hepatitis B needs regular monitoring.

“But I feel healthy, so I can’t have hepatitis B.”

Most people with chronic hepatitis B feel completely well for years. A simple blood test is the only way to know.

Your next step: check that every child in your family has had the hepatitis B vaccine, and ask for a test if you have never had one.

Related: Fatty liver disease · Needlestick injury: what to do

Source: World Health Organization, hepatitis B fact sheet and Global hepatitis report 2024.

Joshua Ibukunoluwa Adebanjo

Founder & Editor-in-Chief

Joshua Ibukunoluwa Adebanjo

RN, RM, RPHN, BNSc (Obafemi Awolowo University)

Joshua is a registered nurse, midwife and public health nurse with clinical experience at Obafemi Awolowo University Teaching Hospitals Complex. He founded Nursing Media Network to give nurses worldwide trustworthy news, career guidance and a stronger public voice, and leads its editorial direction.

Full profile · Editorial policy · joshuadebanjo.com

Health information on Nursing Media Network is for education and does not replace advice from your own nurse or healthcare provider.

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