How to Use an Adrenaline Auto-Injector

An adrenaline auto-injector can save a life during anaphylaxis. Learn the signs of a severe allergic reaction, how to use the pen step by step and what to do afterwards.

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Edited by Joshua Adebanjo, RN

How to Use an Adrenaline Auto-Injector

In anaphylaxis, minutes matter. Adrenaline is the first and most important treatment, and an auto-injector lets anyone give it quickly. If someone you know carries one, learning how to use it could save their life.

Imagine your friend’s lips swelling at a restaurant, then her voice going hoarse and her breathing becoming noisy. She fumbles for her pen. You’ve practised with a trainer pen, so you take it, press it firmly into her outer thigh and call an ambulance. Within minutes her breathing eases.

Signs of anaphylaxis

  • Airway: swollen tongue or throat, hoarse voice, difficulty swallowing
  • Breathing: wheeze, persistent cough, noisy or difficult breathing
  • Circulation: dizziness, collapse, pale or floppy (in children)

Hives, swelling of lips or eyes and vomiting may also appear, but some people have no skin signs. If in doubt, give adrenaline.

Using the pen: general steps

  1. Remove the safety cap (check your brand’s instructions, as designs differ).
  2. Hold the pen in your fist, tip pointing down. Never put your thumb over either end.
  3. Press the tip firmly into the outer middle of the thigh. It works through clothing.
  4. Hold in place for the time stated on the device (often 3 to 10 seconds).
  5. Remove and gently massage the area if advised by the manufacturer.
  6. Call emergency services and say “anaphylaxis”.

But what happens afterwards?

  • Lay the person flat with legs raised. If breathing is hard, let them sit up. Don’t let them stand or walk.
  • If there’s no improvement after 5 minutes, give a second pen if available.
  • Always go to hospital, even if they feel better, because symptoms can return.
  • If they stop breathing, start CPR.

People with severe allergies are usually advised to carry two pens at all times and check expiry dates regularly.

Your next step: If you or someone close carries a pen, watch the manufacturer’s training video and practise with a trainer pen this week.

Sources: Resuscitation Council UK (Anaphylaxis), World Allergy Organization, Anaphylaxis UK, Australasian Society of Clinical Immunology and Allergy (ASCIA).

Joshua Ibukunoluwa Adebanjo

Founder & Editor-in-Chief

Joshua Ibukunoluwa Adebanjo

RN, RM, RPHN, BNSc (Obafemi Awolowo University)

Joshua is a registered nurse, midwife and public health nurse with clinical experience at Obafemi Awolowo University Teaching Hospitals Complex. He founded Nursing Media Network to give nurses worldwide trustworthy news, career guidance and a stronger public voice, and leads its editorial direction.

Full profile · Editorial policy · joshuadebanjo.com

Health information on Nursing Media Network is for education and does not replace advice from your own nurse or healthcare provider.

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